To hope or not to hope?

The next cycle I went early for a check-up and we discussed the options again with the doctor. As we weren’t considering an egg donor just yet, we had to choose between trying another cycle of ovarian stimulation or a natural cycle. The advantage of the stimulation was the possibility of producing more than one mature egg, the disadvantage being the overdose of hormones coming into my body. The doctor didn’t think using the same method as before would give different results but he believed a different treatment could, so we chose that route.

This time I had to self-inject even more drugs and take pills, but I was getting used to it by now. I’m not particularly afraid of needles and didn’t find it that uncomfortable.

At the next appointment we had a great surprise. My ovaries had at least 3 eggs that were growing rapidly. The doctor was as surprised and excited as me. This meant that we could potentially continue with extraction, fertilization and insemination if we wanted to. However, the chances with only 3 eggs were still low.

We had to decide if we were going to go through the full cycle this time, as one of the drugs’ side effects was the thinning of my endometrium. If we chose to go full cycle, we could stop that drug and still continue the stimulation process. We decided not to try for a full cycle this time. We had already expected not to be able to do it at this time, and we wanted to get more eggs to increase our chances when we used the IVF cycle.

I continued with all the drugs until the expected extraction day and was given one last shot that would trigger a release of the egg from the follicle shell in 36 hours. It’s kind of amazing how perfect the body machine is, and how medicine can play along.

The day of the procedure I came to the clinic early, was given a robe and booties and taken to a cubicle to wait. After getting an IV I was rolled into the OR and sedated. Half an hour later I was completely awake, back at the cubicle.

The process managed to obtain 2 mature eggs and we left them frozen waiting for our next visit.

A few weeks earlier my husband had left a semen sample as he had to go back home. Sometimes I think of my eggs and his sperm, frozen in the same room, next to each other, but still separated. Just waiting anxiously for the party to start…

Pulled down to earth… again

Not in a hopeful mood like last time, we just returned from the clinic were we cancelled the first IVF cycle. With only one follicle in my ovaries, and not even the expected size after 8 days of hormonal stimulation, the doctor says there is no point in proceeding this cycle. The news is devastating, even though we knew all along that my ovaries weren’t doing great.

The doctor asks what we think of an egg donor, since this alternative is included in the price of the treatment. Unfortunately, we don’t quite agree on this point. Same as when we considered adoption, I have no problem with not sharing any genetic material with my child, but my husband is still reluctant about that point. Even though, it’s MY genetic material that wouldn’t be part of the child.

Our next step will be to follow closely on the next natural cycle and see if my body produces a useful egg naturally. They can then extract it and keep it frozen. We can do this several times before we go to fertilization, which is when the first IVF cycle would be considered spent. For our lives, it means that my time here in Colombia for now won’t include an insemination, just an egg extraction in the best case. It means we need to plan our schedules and return again in a few months after I’ve completed a few work trips in September and work commitments in October.

Even in my realistic mind, I was almost convinced that two cycles would end in a successful pregnancy and we were going to return with one more life in tow. The reality check is hard and it leaves an open-ended question about when and how we will become parents. Because we will…

Granadillas and Gonal-F

Here we go. The last time we went to Colombia was 3.5 years ago. There is a lot of excitement aside from the medical adventure we’re about to embark on. The doctor has been prescribing tests and medicine that I needed to get before I arrive and everything is in order. I’m taking contraceptives again so we can schedule my cycle precisely when I arrive. My husband and I are in the process of packing and re-packing bags because we bought too many gifts to bring to family members. It’s Saturday June 15th 2019 and we are finally flying home.

The doctor sees me the next day and explains the process again with drawings and photographs. After a sonogram, everything looks good. I go back to the clinic on Monday to get additional bloodwork done and to get the ovarian stimulating medicine, Gonal-F, and Letrozole pills. I stop the contraceptive pills and we have to wait for 5 days for my cycle to regulate again. On Saturday morning I’m half nervous about self-injecting the drug in my belly, and half excited with the official beginning of the process. Like clock-work, I got my period overnight. The injection turns out to be nothing, aside from a little sore belly afterwards, but my happiness returns when I go grocery shopping and buy granadillas. I’ve missed this little fruit so dearly for the past 3.5 years! This slimy and crunchy, and visually unappealing fruit makes my day.

We have now started the first of 4 IVF cycles (we chose the 4-cycle plan which includes everything for $10,000). We are mentally prepared to go through more than one, but really hoping this first one is the one. Being at home, away from work and with our parents, is also helpful for the emotional roller coaster that this is.

Today, with a little science and a lot of hope, we are submitting one more request to the stork!

Bring out the big guns?

Three years had gone by since we made our decision to have a kid. Now at 37, my obgyn refers me to a fertility clinic. During the first appointment the doctor explains the options very clearly. He even makes me repeat them to him to make sure I understand. We can try IUI (intrauterine insemination) for one or more cycles, or skip that and go to IVF (in-vitro fertilization). The recommendation will be dependent on the tests.

The tests come back and the news are not very encouraging. I’m almost out of follicles inside my ovaries, which means IUI might be a waste of time and he recommends IVF. But, after the good first impression, I find myself having to call the clinic to get the test results mailed to me, because it is not their standard practice to give the results to the patients. The doctor does not see me again after the results, only gives me a call. So, I’m faced with the decision to spend $25,000 dollars on one IVF cycle at a clinic that has not spent any time going over the test results with us (where I already spent $2,000 on tests). At this point we backpedaled fast and I start thinking about other options.

I spend hours researching about adoption. The more I read about it, the more excited I am with the idea of giving a chance to a child that might not get it otherwise. My first idea is to adopt in my home country, Colombia, but I find out that the US does not allow me to bring an adopted child, because I’m not an American Citizen. We still continue with the search, go to adoption fairs, go through adoption training and end up with mixed feelings. Most of the children that are given up for adoption in my country come from poverty, but they are healthy otherwise. Most children that go for adoption in the US come from drug and alcohol addicted mothers and have serious conditions derived from that. It is scary and my husband is not as ready to continue down this path now that we know the challenges.

Demoralized, I find another OBGYN who has a fertility background and at my next routine check-up, she recommends repeating all bloodwork (it’s been a year). The results are very similar, however, the AMH has increased. AMH is related to ovarian reserve, and it’s not supposed to increase, ever. In my case, it went from 0.04 to 0.43. It’s still low but it is a significant and unexplained increase. In the year between the two tests, after giving up on fertility treatment with the first clinic, I read about natural and alternative methods and foods to improve fertility. I bought royal jelly, pollen caplets, and other products that I read about, and I can only attribute the increase to them. However, the recommendation is still to go for IVF.

At this point we are stuck with the impossibility to adopt a healthy child in Colombia, the high cost of IVF in the US and the distrust in the clinics that we have to choose from. I start talking to my doctor from Colombia and he recommends that I go home for the treatment, at a better clinic and for a fraction of the cost. The logistics are complicated since it means to go home for a couple of months but even the salary loss is less that the total cost in the US. I get connected to a doctor and start learning about how the process is done in Colombia. Without having paid even a doctor’s visit, I have already spent a few hours talking about the process with the doctor, all the details and options are quoted by the clinic (in actual written documents). I finally start seeing a little glow at the end of this long tunnel.

Lesson number 4: there are many options, from conception to adoption, different methods and treatments, and plenty of doctors, clinics and agencies. It’s easy to get demoralized by a wrong choice or unexpected result, but at least one of the many options will be right for you. With so many undesired kids being brought into this world, those of us that truly want them should not give up, ever.

Learning more about the process

After 35, the chance of having a miscarriage is 20%. Most of the time they’re caused by genetic abnormalities, and the father’s age is also a factor. Many times a miscarriage occurs at the time you’re expecting your next period and you assume it’s just a heavy period. I’m sure I’ve had several of those. After such a long time of trying to conceive I’m in the habit of observing carefully everything in my body.

So, having a miscarriage still early in the trying-to-conceive journey was like hitting a wall, but it made me start reading about it. Reading about the causes, the statistics, and understanding better that the process should really not be left to chance anymore. Having a sex life and not using birth control are not enough.

So, I had just gone through a painful process and several months went by before it was time for my yearly obgyn visit. At this time, I had been trying to conceive for 2 years and he recommended a semen analysis for my husband and to start using over the counter ovulation kits.

My husband’s semen was good and I started peeing on a stick every morning to detect the peak of ovulation. These kits come in a wide range of prices. I chose one that was sort of expensive, from a known brand, and used it for many months. More importantly, I kept track of the results to find patterns. I started using the Glow App to track all sorts of things: ovulation, period, sexual activity, physical symptoms…

It is exhausting. Measuring and tracking things, calculating, waiting for two weeks every month for a new deception. But what I found the most exhausting is that sex turned into a reproductive act and it got to the point where I had to press my husband to have sex because, believe me, it gets tiring when it’s not about the mood and you’re just following schedule.

Lesson number 3: my biggest mistake was to take all the education on my own and not include my husband along the way. (His mistake, off course, was to let me do it alone). After many months I started explaining to him why we had to be on such a strict schedule if we ever wanted to get pregnant and by then we were both exhausted and demoralized. After talking to many friends who are going through the same process, I’ve found that it is not uncommon for the men to just let the women deal with it alone. They just have sex whenever they’re told but they’re not part of tracking, and scheduling, and waiting anxiously. They should be.

Now it’s easy, right?

After a year of deciding we wanted to have kids, we were finally able to start trying. Vaccines were in order, no more birth control and you think that’s all, right? When we’re young we’re led to believe that if you have sex any time one week before or after the 14th day of your cycle, then you’ll likely get pregnant. With the birth control off, nothing could stop us from getting pregnant in a month or two.

Maybe it was just me, but I didn’t think I needed to take any special measures to get pregnant. My obgyn had told me with an accusing stare at some point in the past that my eggs were created when I was in the womb. So, my eggs are kind of old, I thought. He didn’t bother really explaining that their number also rapidly decreases in the mid 30’s and many other things start changing in the reproductive system. Some people actually study biology and know these things already, for most of us, even if the information was received in high school at this level of detail, we’d have forgotten 20 years later.

After just a few months of trying to get pregnant (by simply stopping birth control), we had to go through some major changes, big move, job and such, and when things finally settled we got pregnant. Oh, it was just the stress that was affecting me off course, I assumed.

However, because we were not really “actively trying”, and I hadn’t read anything about pregnancy symptoms, I didn’t realize I was pregnant initially. I spent an entire night throwing up and blamed it on the food, then spotted at the time I was expecting my period and assumed it was just a light period, then my breasts were sore… and I started putting it all together.

I was 7 weeks pregnant when I went to the doctor and had a sonogram. There was no embryo. It is called a blighted ovum. You have all the symptoms, the tests are positive, you have a placenta sac, but no embryo. I was devastated. By then I had devoured 3 pregnancy books, installed 2 apps, bought grandparent coffee mugs for my parents, prepared how to give them the news…

I had to get an induced miscarriage, which was painful and emotionally draining. But then my body started cycling again pretty fast and on a positive note I kept thinking “I actually got pregnant once so I should be able to again”.

Lesson number 2: It takes precision to get pregnant. An egg is released and travels the tubes and uterus in a couple of hours and gets expelled. It needs to encounter sperm during that short time. This means having sperm already in your body 1-2 days before (yes, it typically lives that long). How long sperm can live inside your body changes from woman to woman. So, if you don’t have sex for 2 consecutive days you could have entirely missed the chance!

The Right Time

I always knew I wanted to be a mother. No question in my mind. I have a super-mom, really one of the great ones, and I was always convinced motherhood was one of the greatest things and not just a thing society expects of women. On the other hand, I come from a family of mostly high-achievers in education and career matters. I knew after high school I’d go to college and then a graduate degree. I didn’t always plan to get a doctoral degree but I did end up all the way there.

So, you start putting your plans in schedule. Go to school, work and travel before 30. Then get married at some point and then the kids. That pushes you easily into the after-35 downward slope of fertility. But I never knew there was such a steep decline. You always hear about women getting pregnant after 40 so you think it’s common, even if it’s still commented by people.

My husband and I moved in together when I was 28 and got married 2 years later. I was in the middle of my PhD at the time so I was on the pill. At 33 I finished my studies but we waited another year for things to settle.

Finally it was time. I was 34 and felt that it was a great time to get pregnant. I went to my obgyn and told him we wanted to have kids now. He gave me some blood work to make sure I was not in risk of infectious diseases and found out that my chickenpox vaccine (from some years before) didn’t work, for some reason, and I wasn’t immune. I went to get vaccinated, they recommended 2 doses which means waiting for 3 months between them. Then the vaccine was not available anywhere for a few months and finally about 9 months went by. I could have had a kid in the time it took to go through this immunization.

Lesson number one: Don’t wait until you’re ready to conceive to find out you’re missing an important vaccine, or have a vitamin deficiency, or anything that can be easily fixed but could take time. You could tell your doctor you want to have kids in a few years and s/he can start evaluating those things.

It all started… a little too late

So, here is the deal. I’m almost 40, about to embark in the biggest process to conception with the help of science, called 4-cycle IVF, and I’m actually feeling pretty optimistic, even though this is the 6th year of my trying-to-conceive life.

I realize I’ve learned so much and also, I had no idea of how conception really works until I set up to try it myself. This is not an education we get normally. Not in my culture, in my generation, but I’m sure it applies to many other women and certainly men around the globe. Yes, I said men, because this is typically not a one-person plan even though it can be (but then you’d be skipping most of the steps I took first and go directly to the help of science).

I wish I had been writing this blog all along. Now I’ll attempt to reconstruct everything I went through in a series of articles. If you are a person of any age that hopes to be a biological parent at some point in the future, you can learn something from my experience or share yours.

Welcome to this stork’s journey!